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Welcome to the Holiday Inn Guin, AL. We are centrally located between Memphis, Tennessee and Birmingham, Alabama; we can meet you in the middle, and a short drive from Tupelo, MS. This Alabama hotel will help maintain your exercise regimen in our fitness center. Take a swim in our pool or relax at our outdoor patio. Catch up on work in our business center. The Grille 22 serves breakfast, lunch and dinner daily.